issue contents
September 2024 issue

Cover illustration: The GDP-bound human M-RAS protein, crystal form I [Bester et al. (2024), Acta Cryst. F80, 220–227]. M-RAS, a monomeric GTPase protein, serves as a signaling protein and acts as a molecular switch to regulate cellular transformation. It dynamically cycles between an inactive GDP-bound state and an active GTP-bound state. The transitions between the inactive and active states are essential for interaction with effectors that mediate signaling pathways.
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