issue contents

ISSN: 2052-2525

November 2021 issue

Early view articles

Journal cover

research papers


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Samples for single-particle cryo-electron microscopy can be routinely vitrified using only liquid nitro­gen at its boiling temperature, allowing sample handling workflows to be simplified and sample stresses that contribute to beam-induced motion to be reduced.


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Higher X-ray energies are experimentally demonstrated to be highly beneficial for macromolecular crystallography.


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MltA from the human pathogen Acinetobacter baumannii was characterized and its dimeric crystal structure was unveiled, demonstrating the extra-domain-mediated dimerization of MltA for the first time. Based on the current structural and biochemical studies, the working mechanism of MltA with various functionally related proteins on the bacterial outer membrane was modeled.
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