November 2012 issue
Cover illustration: Having enhanced potency, selectivity, and duration of action, the title opioid salvinorin A derivative, C23H30O8, also exhibits surprising structural mimicry with salvinorin A. This arises as the ether residue adopts a gauche-gauche conformation which traces a helix around the acetate group of salvinorin A. See: Munro, Ho & Cohen [Acta Cryst. (2012). E68, o3225-o3226].