issue contents
December 2015 issue
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Cover illustration: The compound C19H22N2O3 is the 5-bromopyrimidine derivative of Parthenolide (PTL). PTL has been isolated from several different plant species, feverfew leaf (Tanacetum parthenium) being one of the major sources. It is a sesquiterpene lactone known to significantly target cancer stem cells. In order to obtain detailed information on the structural conformation of the title compound, including assignment of the absolute configuration of the four stereocentres, and to establish the geometry of the exocyclic double bond, a single crystal X-ray structure determination has been carried out. See: Bommagani, Penthala, Parkin & Crooks [Acta Cryst. (2015). E71, 1536-1538].
research communications
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data reports
metal-organic compounds
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organic compounds
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